Welcome to Alexandrov lab
Identification of Disease-Associated Human RNA Pathways
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We are state of the art-equipped lab in the Clemson Center for Human Genetics. We use forward genetics to identify and study disease-associated human pathways of RNA biogenesis, regulation, and surveillance.
To conduct forward genetic interrogation of RNA pathways, we use ultra high-throughput methods that employ CRISPR-based mutagenesis of the human genome and FACS (fluorescence-activated cell sorting). The RNA pathways we are focusing on play critical roles in (a) cancer and (b) genetic diseases that arise from mutations resulting in a premature termination codon. Among cancer-associated human RNA pathways, we are currently focusing on those regulating levels of the human nuclear long non-coding RNA MALAT1. |
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Research Opportunities:
- Graduate PhD students interested in research in our lab while being Teaching Assistants (TA) in the Dept. of Genetics and Biochemistry, please email andreia@clemson.edu to schedule your (i) zoom meeting/lab visit and (ii) first semester rotation with us. Please note that we are not on the main Clemson campus. Our lab is in the Clemson University's Center for Human Genetics in Greenwood, SC.
- Master Students (MS) interested in thesis research in our lab, please email andreia@clemson.edu to schedule your zoom meeting/lab visit.
- We are sorry, all our graduate PhD Research Assistant (RA) positions are currently filled. Whenever available, openings will be posted here.
- Master Students (MS) interested in thesis research in our lab, please email andreia@clemson.edu to schedule your zoom meeting/lab visit.
- We are sorry, all our graduate PhD Research Assistant (RA) positions are currently filled. Whenever available, openings will be posted here.
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Contact: Andrei Alexandrov, PhD Assistant Professor of Genetics and Biochemistry Clemson University Center for Human Genetics Self Regional Hall, Rm 134 114 Gregor Mendel Circle Greenwood, SC 29646 (203)-848-9835 andreia@clemson.edu www.alexandrovlab.com/ |
Genetics & Biochemistry at Clemson University: www.clemson.edu/science/departments/genetics-biochemistry/people/profiles/andreia
Clemson Center for Human Genetics (Greenwood, SC): scienceweb.clemson.edu/chg/people/
Clemson Center for Human Genetics (CHG) on Twitter: twitter.com/clemsonchg
Clemson Center for Human Genetics (Greenwood, SC): scienceweb.clemson.edu/chg/people/
Clemson Center for Human Genetics (CHG) on Twitter: twitter.com/clemsonchg
