Welcome to Alexandrov lab

Identification of Disease-Associated Human RNA Pathways 

    We are state of the art-equipped lab in the Clemson Center for Human Genetics. We use forward genetics to identify and study disease-associated human pathways of RNA biogenesis, regulation, and surveillance.
     To conduct forward genetic interrogation of RNA pathways, we use ultra high-throughput methods that employ CRISPR-based mutagenesis of the human genome and FACS (fluorescence-activated cell sorting).  
    The RNA pathways we are focusing on play critical roles in (a) cancer and (b) genetic diseases that arise from mutations resulting in a premature termination codon. 
    Among cancer-associated human RNA pathways, we are currently focusing on those regulating levels of the human nuclear long non-coding RNA MALAT1. 

​Research Opportunities:

- We are sorry, all our graduate PhD Research Assistant (RA) positions are currently filled. When available, openings will be posted here.
- Master Students (MS) interested in thesis research in our lab, please email [email protected] to schedule your zoom meeting/lab visit. 

Contact:
Andrei Alexandrov, PhD
​Assistant Professor of Genetics and Biochemistry
Clemson University 
​Center for Human Genetics
Self Regional Hall, Rm 134
114 Gregor Mendel Circle
Greenwood, SC 29646
(203)-848-9835
[email protected]
www.alexandrovlab.com/

Genetics & Biochemistry at Clemson University: www.clemson.edu/science/departments/genetics-biochemistry/people/profiles/andreia
Clemson Center for Human Genetics (Greenwood, SC): scienceweb.clemson.edu/chg/people/
Clemson Center for Human Genetics (CHG) on Twitter: twitter.com/clemsonchg