Welcome to Alexandrov lab
Identification of Disease-Associated Human RNA Pathways
We are state of the art-equipped lab in the Clemson Center for Human Genetics. We use forward genetics to identify and study disease-associated human pathways of RNA biogenesis, regulation, and surveillance.
To conduct forward genetic interrogation of RNA pathways, we use ultra high-throughput methods that employ CRISPR-based mutagenesis of the human genome and FACS (fluorescence-activated cell sorting). The RNA pathways we are focusing on play critical roles in (a) cancer and (b) genetic diseases that arise from mutations resulting in a premature termination codon. Among cancer-associated human RNA pathways, we are currently focusing on those regulating levels of the human nuclear long non-coding RNA MALAT1. |
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Research Opportunities:
- We are sorry, all our graduate PhD Research Assistant (RA) positions are currently filled. When available, openings will be posted here.
- Master Students (MS) interested in thesis research in our lab, please email [email protected] to schedule your zoom meeting/lab visit.
- Master Students (MS) interested in thesis research in our lab, please email [email protected] to schedule your zoom meeting/lab visit.
Contact: Andrei Alexandrov, PhD Assistant Professor of Genetics and Biochemistry Clemson University Center for Human Genetics Self Regional Hall, Rm 134 114 Gregor Mendel Circle Greenwood, SC 29646 (203)-848-9835 [email protected] www.alexandrovlab.com/ |
Genetics & Biochemistry at Clemson University: www.clemson.edu/science/departments/genetics-biochemistry/people/profiles/andreia
Clemson Center for Human Genetics (Greenwood, SC): scienceweb.clemson.edu/chg/people/
Clemson Center for Human Genetics (CHG) on Twitter: twitter.com/clemsonchg
Clemson Center for Human Genetics (Greenwood, SC): scienceweb.clemson.edu/chg/people/
Clemson Center for Human Genetics (CHG) on Twitter: twitter.com/clemsonchg