Welcome to Alexandrov lab

Identification of Disease-Associated Human RNA Pathways 

    We are state of the art equipped lab in the Clemson Center for Human Genetics. We use forward genetics to identify and study disease-associated human pathways of RNA biogenesis, regulation, and surveillance.
     To conduct forward genetic interrogation of RNA pathways, we use ultra high-throughput methods that employ CRISPR-based mutagenesis of the human genome and FACS (fluorescence-activated cell sorting).  
    The RNA pathways we are focusing on play critical roles in (a) cancer and (b) genetic diseases that arise from mutations resulting in a premature termination codon. 
    Among cancer-associated human RNA pathways, we are currently focusing on those regulating levels of the human nuclear long non-coding RNA MALAT1. 

​Jobs/Research Opportunities (please email andreia@clemson.edu to inquire):

- One full-time job position: Research Technician (starts: July, 2021).
- Research assistantships (RA) for highly motivated Graduate Students (PhD) to conduct cutting-edge thesis research in our lab.
- Research opportunities for Master Students (MS) interested in RNA biology, CRISPR, and mutational interrogation of the human genome.
Sorry Folks, all three Summer Undergraduate positions are already filled for 2021. Please, stay tuned for the Summer of 2022.

Contact:
Andrei Alexandrov, PhD
​Assistant Professor of Genetics and Biochemistry
Clemson University 
​Center for Human Genetics
Self Regional Hall, Rm 134
114 Gregor Mendel Circle
Greenwood, SC 29646
(203)-848-9835
andreia@clemson.edu
www.alexandrovlab.com/

Clemson Center for Human Genetics (Greenwood, SC): scienceweb.clemson.edu/chg/people/
CHG Twitter: twitter.com/clemsonchg
Genetics & Biochemistry at Clemson University: www.clemson.edu/science/departments/genetics-biochemistry/people/profiles/andreia